The Reason Some People Can’t Hold Their Drink
By Jeremy Dean
It's true: some people really can't hold their drink.
A gene has been identified which may help to explain why some people can’t hold their drink.
Most people know someone who only has to have a little alcohol to make them start acting very strangely.
The genetic mutation, which affects a receptor called serotonin 2B, has been identified by Finnish researchers.
Dr Roope Tikkanen, who led the research, said:
“The results also indicate that persons with this mutation are more impulsive by nature even when sober, and they are more likely to struggle with self-control or mood disorders.”
The serotonin 2B receptor is thought to be linked to impulsivity.
The mutation is present in around 2.2% of people.
Dr Tikkanen said:
“The impact of one gene on complex phenomena is typically minor.
But it is possible to identify the impact of such a genetic mutation in the Finnish population, as our historical isolation has led to a relatively homogenous gene pool.”
The study was published in the journalTranslational Psychiatry (Tikkanen et al., 2015).
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